Table 1 Bioactivity of the rec-eCGβ/α and native eCG in CHO-K1 cells expressing eelLH/CGR
| eCG type CHO-K1 cells (transient) | cAMP responses |
| Basal (nM / 104 cells) | EC50 (ng/mL) | Rmax (nM / 104 cells) |
| Rec-eCGβ/α | 0.53 | 172.4 (118 to 251) | 19.6 |
| Native eCG | 1.54 | 786.6 (527 to 1,174) | 14.54 |
Values are the means of triplicate experiments. The EC50 values used to determine the potency were obtained from the concentration-response curves for the in vitro bioassays.
rec-eCGβ/α, recombinant equine chorionic gonadotropin ; eCG, equine chorionic gonadotropin; cAMP, cyclic adenosine monophosphate; EC, effective concentration.