No. of cycles initiated | 30 | 30 | 30 | 30 |
No. of cycles retrieved | 28 | 29 | 30 | 30 |
No. of ET cycles | 27 | 28 | 30 | 30 |
No. of cycles cancelled | 3 (10.0%) | 2 (6.7%) | 0 | 0 |
On stimulation day 1 | | | | |
AFC | 4.0 ± 1.3 | 4.1 ± 1.2 | 4.9 ± 1.1a | 5.2 ± 1.0b |
MFD | 5.9 ± 0.6 | 5.7 ± 0.5 | 5.2 ± 0.4c | 4.7 ± 0.4c |
RI of OSA | 0.95 ± 0.03 | 0.94 ± 0.03 | 0.92 ± 0.03d | 0.89 ± 0.03c |
Total dose of rhFSH (IU) | 3,025.0±425.9 | 2,765.7±567.8 | 2,596.7±335.3c | 2,643.5±389.0c |
Days of rhFSH administered | 10.6±1.5 | 10.2±1.7 | 9.6±1.1c | 9.8±1.0c |
No. of oocytes retrieved | 3.9±1.3 | 4.3±1.6 | 5.3±2.0c | 5.8±1.9c |
No. of mature oocytes | 3.1±1.1 | 3.6±1.3 | 4.5±1.8c | 4.9±1.6c |
No. of fertilized oocytes | 3.1±1.1 | 3.5±1.3 | 4.2±1.7c | 4.6±1.6c |
No. of grade I, II embryos | 1.5±0.6 | 1.6±0.6 | 2.2±0.6a | 2.1±0.7a |
No. of embryos transferred | 2.9±0.9 | 2.7±0.7 | 2.9±0.9 | 2.9±0.8 |
CPR per cycle initiated (%) | 10.0 (3/30) | 16.7 (5/30) | 30.0 (9/30) | 36.7 (11/30)e |
Miscarriage rate per clinical pregnancy (%) | 33.3 (1/3) | 20.0 (1/5) | 22.2 (2/9) | 18.2 (2/11) |
Live birth rate per cycle initiated (%) | 6.7 (2/30) | 13.4 (4/30) | 20.0 (6/30) | 30.0 (9/30)f |
Multiple pregnancy rate (%) | 0 | 0 | 22.2 (2/9) | 18.2 (2/11) |