Table 2.
Comparison of controlled ovarian stimulation results and IVF-ET outcome

Control 2 wks treatment 3 wks treatment 4 wks treatment
No. of cycles initiated 30 30 30 30
No. of cycles retrieved 28 29 30 30
No. of ET cycles 27 28 30 30
No. of cycles cancelled 3 (10.0%) 2 (6.7%) 0 0
On stimulation day 1
AFC 4.0 ± 1.3 4.1 ± 1.2 4.9 ± 1.1a 5.2 ± 1.0b
  MFD 5.9 ± 0.6 5.7 ± 0.5 5.2 ± 0.4c 4.7 ± 0.4c
  RI of OSA 0.95 ± 0.03 0.94 ± 0.03 0.92 ± 0.03d 0.89 ± 0.03c
Total dose of rhFSH (IU) 3,025.0±425.9 2,765.7±567.8 2,596.7±335.3c 2,643.5±389.0c
Days of rhFSH administered 10.6±1.5 10.2±1.7 9.6±1.1c 9.8±1.0c
No. of oocytes retrieved 3.9±1.3 4.3±1.6 5.3±2.0c 5.8±1.9c
No. of mature oocytes 3.1±1.1 3.6±1.3 4.5±1.8c 4.9±1.6c
No. of fertilized oocytes 3.1±1.1 3.5±1.3 4.2±1.7c 4.6±1.6c
No. of grade I, II embryos 1.5±0.6 1.6±0.6 2.2±0.6a 2.1±0.7a
No. of embryos transferred 2.9±0.9 2.7±0.7 2.9±0.9 2.9±0.8
CPR per cycle initiated (%) 10.0 (3/30) 16.7 (5/30) 30.0 (9/30) 36.7 (11/30)e
Miscarriage rate per clinical pregnancy (%) 33.3 (1/3) 20.0 (1/5) 22.2 (2/9) 18.2 (2/11)
Live birth rate per cycle initiated (%) 6.7 (2/30) 13.4 (4/30) 20.0 (6/30) 30.0 (9/30)f
Multiple pregnancy rate (%) 0 0 22.2 (2/9) 18.2 (2/11)
Values are means ± standard deviations. ET = embryo transfer; AFC = antral follicle count; MFD = mean follicular diameter; RI = resistance index; OSA = ovarian stromal artery; rhFSH = recombinant human follicle stimulating hormone; CPR = clinical pregnancy rate
p<0.050 vs control group
p=0.002 vs control group
p<0.001 vs control group
p<0.010 vs control group
p=0.030 vs control group
p=0.042 vs control group